Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552159 | 0.85 | TRPV1 (0.48) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2623146 | 0.83 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1ALOX12KDM4E | |
| SCHEMBL1970070 | 0.82 | GDA (0.58) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL6937511 | 0.82 | KMT2A (0.47) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL3236094 | 0.82 | ALOX15 (0.58) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL1425017 | 0.79 | ADORA2A (0.52) | NPC1RAB9ATP53SMN1; SMN2MAPT | |
| SCHEMBL12227604 | 0.78 | GDA (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28472801 | 0.78 | ROCK2 (0.47) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL25921184 | 0.77 | GAA (0.56) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL30208590 | 0.76 | TERT (0.38) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-05-14 | — | — | US | claimed |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-11-24 | — | — | US | claimed |
| EP-2334692-B1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | UNIV MCGILL (CA) | 2016-04-13 | — | — | EP | claimed |
| US-9249175-B2 | RNA monomers containing O-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTE FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-02-02 | — | — | US | claimed |
| US-20120178638-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-12 | — | — | US | claimed |
| EP-2334692-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2011-06-22 | — | — | EP | claimed |
| WO-2010025566-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2010-03-11 | — | — | WO | claimed |
| EP-2862868-B1 | INTERMEDIATE FOR PRODUCTION OF NUCLEOSIDE ANALOGUE, AND METHOD FOR PRODUCING SAME | DAIICHI SANKYO CO LTD (JP) | 2020-04-08 | — | — | EP | disclosed |
| US-9738681-B2 | Intermediate for production of nucleoside analog and method for producing the same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-08-22 | — | — | US | disclosed |
| US-20160068561-A9 | Intermediate for Production of Nucleoside Analog and Method for Producing the Same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-03-10 | — | — | US | disclosed |
| US-20150152132-A1 | Intermediate for Production of Nucleoside Analog and Method for Producing the Same | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-06-04 | — | — | US | disclosed |
| EP-2862868-A1 | INTERMEDIATE FOR PRODUCTION OF NUCLEOSIDE ANALOGUE, AND METHOD FOR PRODUCING SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | EFTUD2, RNMT, NSUN2 | NPC1 4871/4885RAB9A 4371/4885TP53 2717/4885 |
| US-20150152132-A1 | Intermediate for Production of Nucleoside Analog and Method for Producing the Same | RNGTT, NSUN2, RNMT | NPC1 1755/4885RAB9A 3756/4885TP53 2864/4885 |
| US-20160068561-A9 | Intermediate for Production of Nucleoside Analog and Method for Producing the Same | RNGTT, NSUN2, RNMT | NPC1 1755/4885RAB9A 3756/4885TP53 2864/4885 |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | NPC1 4873/4885RAB9A 4368/4885TP53 2504/4885 |
| US-20120178638-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | NPC1 4873/4885RAB9A 4368/4885TP53 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.