Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700987 | 0.93 | CYP1A2 (0.58) | RECQLCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27528801 | 0.86 | MTNR1A (0.53) | RECQLCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10552333 | 0.83 | L3MBTL1 (0.59) | RECQLCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14317565 | 0.83 | MTNR1A (0.50) | RECQLCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16673237 | 0.82 | ALDH1A1 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL38664 | 0.82 | LTA4H (0.60) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL868517 | 0.81 | THRB (0.59) | RECQLRAB9ANPC1KMT2ATP53 | |
| SCHEMBL1811389 | 0.81 | RAB9A (0.59) | RECQLCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9602821 | 0.81 | ALOX15 (0.59) | RECQLRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL25282287 | 0.80 | THRB (0.57) | RECQLRAB9ANPC1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |