Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 4/20 | 0.36 |
| ▸ | EDNRA | P25101 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287094 | 0.85 | RAB9A (0.43) | KMT2AAPLNRRAB9APKMDRD2 | |
| SCHEMBL30393256 | 0.85 | RAB9A (0.43) | KMT2AAPLNRRAB9APKMDRD2 | |
| SCHEMBL1415192 | 0.82 | CA12 (0.39) | KMT2AAPLNRCA12CA1CA9 | |
| SCHEMBL15085977 | 0.81 | APLNR (0.45) | KMT2AAPLNRALPLCA12CA1 | |
| SCHEMBL4816617 | 0.80 | DRD2 (0.45) | EDNRBEDNRAALPLRAB9ADRD2 | |
| SCHEMBL14573872 | 0.80 | FFAR1 (0.38) | KMT2ACA12CA1CA9DRD2 | |
| SCHEMBL61072 | 0.80 | ALDH1A1 (0.42) | CA12CA1CA9RAB9ADRD2 | |
| SCHEMBL941194 | 0.80 | DRD2 (0.40) | EDNRBEDNRAALPLRAB9ADRD2 | |
| SCHEMBL28480864 | 0.80 | ALOX15 (0.44) | KMT2AAPLNRPKMALDH1A1 | |
| SCHEMBL14992971 | 0.80 | HTR2A (0.36) | KMT2AAPLNRALPLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785692-B1 | SUBSTITUTED ANILINES AS CCR(4) ANTAGONISTS | CHEMOCENTRYX INC (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2668152-B1 | BICYCLIC TRAMADOL DERIVATIVES FOR CONTROLLING PAIN | LILLY CO ELI (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015161014-A1 | HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-8802728-B2 | Analgesic compounds, methods, and formulations | ELI LILLY AND COMPANY (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130225679-A1 | ANALGESIC COMPOUNDS, METHODS, AND FORMULATIONS | ELI LILLY AND COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1164178-B1 | Electroluminescent devices having arylamine polymers | EASTMAN KODAK CO (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-1164178-A1 | Electroluminescent devices having arylamine polymers | EASTMAN KODAK COMPANY (US) | 2001-12-19 | — | — | EP | disclosed |
| US-6329086-B1 | GOOD SOLUBILITY, EFFICIENCY AND STABILITY; EMITTING COLOR OF THE POLYMER CAN BE EASILY TUNED BY THE INCORPORATION OF DESIRED AROMATIC GROUP; POLYARYLENEVINYLENE | EASTMAN KODAK COMPANY | 2001-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225679-A1 | ANALGESIC COMPOUNDS, METHODS, AND FORMULATIONS | OPRL1, OPRK1, OPRM1 | EDNRB 1060/4885EDNRA 817/4885KMT2A 2773/4885 |
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | EDNRB 1648/4885EDNRA 1034/4885KMT2A 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.