Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942683 | 0.86 | ALDH1A1 (0.40) | P2RX7HSP90AA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6945341 | 0.76 | P2RX7 (0.34) | P2RX7HSP90AA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6941692 | 0.72 | STS (0.34) | P2RX7MEN1KMT2AEPHX2 | |
| SCHEMBL6943637 | 0.71 | P2RX7 (0.48) | P2RX7MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7142000 | 0.67 | SCN9A (0.51) | HSD17B10SCN9A | |
| SCHEMBL28144676 | 0.65 | ALDH1A1 (0.39) | MEN1ALDH1A1THRBHTTKMT2A | |
| SCHEMBL7825363 | 0.65 | HSD11B1 (0.49) | P2RX7KDM4EALDH1A1GAAMAPT | |
| Urea SCHEMBL28504047 | 0.65 | DPP4 (0.43) | HSD17B10 | |
| SCHEMBL28347088 | 0.65 | HSP90AA1 (0.37) | HSP90AA1MEN1GAAMAPTKMT2A | |
| SCHEMBL11858437 | 0.64 | ALDH1A1 (0.38) | MEN1ALDH1A1HTTKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | claimed |