Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945341 | 0.85 | P2RX7 (0.34) | P2RX7CNR2KMT2AMEN1FAAH | |
| SCHEMBL6942683 | 0.76 | ALDH1A1 (0.40) | P2RX7KMT2AMEN1FAAHEPHX2 | |
| SCHEMBL6941692 | 0.72 | STS (0.34) | P2RX7CNR2KMT2AMEN1EPHX2 | |
| SCHEMBL6684733 | 0.72 | HTR2A (0.44) | P2RX7CNR2KMT2AMEN1FAAH | |
| SCHEMBL6941696 | 0.71 | P2RX7 (0.40) | P2RX7KMT2AMEN1FAAHEPHX2 | |
| Hydrochloric Acid SCHEMBL6687045 | 0.71 | HTR2C (0.46) | P2RX7CNR2KMT2AMEN1FAAH | |
| SCHEMBL6941341 | 0.65 | P2RX7 (1.00) | P2RX7KMT2AEPHX2 | |
| SCHEMBL6680351 | 0.64 | EPHX2 (0.41) | P2RX7KMT2AMEN1EPHX2SMN1; SMN2 | |
| SCHEMBL28144676 | 0.63 | ALDH1A1 (0.39) | KMT2AMEN1NPC1ALDH1A1HSD11B1 | |
| SCHEMBL6085448 | 0.63 | SMN1; SMN2 (0.54) | P2RX7CNR2KMT2AMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | claimed |