Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942683 | 0.79 | ALDH1A1 (0.40) | P2RX7SMN1; SMN2EPHX2MEN1KMT2A | |
| SCHEMBL6945341 | 0.74 | P2RX7 (0.34) | P2RX7LMNACNR2SMN1; SMN2HSD11B1 | |
| SCHEMBL6941696 | 0.72 | P2RX7 (0.40) | P2RX7EPHX2MEN1KMT2A | |
| SCHEMBL6943637 | 0.72 | P2RX7 (0.48) | P2RX7CNR2SMN1; SMN2POLBHSD11B1 | |
| SCHEMBL6941247 | 0.64 | P2RX7 (0.69) | P2RX7ABCB11 | |
| SCHEMBL28144676 | 0.64 | ALDH1A1 (0.39) | LMNAHSD11B1RAB9AMEN1KMT2A | |
| SCHEMBL11858437 | 0.63 | ALDH1A1 (0.38) | LMNAHSD11B1RAB9AEPHX2MEN1 | |
| SCHEMBL16956564 | 0.62 | SLC6A2 (0.40) | ABL1 | |
| SCHEMBL6680351 | 0.62 | EPHX2 (0.41) | P2RX7LMNASMN1; SMN2POLBHSD11B1 | |
| SCHEMBL8104812 | 0.61 | HSP90AA1 (0.37) | P2RX7CNR2EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | claimed |