Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941696 | 0.86 | P2RX7 (0.40) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL6945341 | 0.81 | P2RX7 (0.34) | ALDH1A1MAPTKDM4EMEN1HPGD | |
| SCHEMBL6941692 | 0.79 | STS (0.34) | MEN1KMT2AP2RX7EPHX2SMN1; SMN2 | |
| SCHEMBL6943637 | 0.76 | P2RX7 (0.48) | ALDH1A1MAPTMEN1KMT2AP2RX7 | |
| SCHEMBL6680351 | 0.66 | EPHX2 (0.41) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28144676 | 0.65 | ALDH1A1 (0.39) | ALDH1A1MEN1THRBHTTKMT2A | |
| SCHEMBL8104812 | 0.65 | HSP90AA1 (0.37) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL28347088 | 0.65 | HSP90AA1 (0.37) | MAPTMEN1GAAKMT2AHSP90AA1 | |
| SCHEMBL11858437 | 0.64 | ALDH1A1 (0.38) | ALDH1A1MEN1HTTKMT2AEPHX2 | |
| SCHEMBL6941223 | 0.63 | P2RX7 (0.70) | P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036058-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2003-03-12 | — | — | EP | claimed |