Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL21981463 | 0.93 | SIGMAR1 (0.85) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| Acetic Acid SCHEMBL7452259 | 0.90 | SIGMAR1 (0.79) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL11207245 | 0.90 | SIGMAR1 (0.79) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL152631 | 0.89 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL83548 | 0.89 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL6138636 | 0.89 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL276363 | 0.89 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| Benzene SCHEMBL27761330 | 0.89 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7573306 | 0.87 | SIGMAR1 (0.96) | SIGMAR1ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8145866 | 0.87 | SIGMAR1 (0.96) | SIGMAR1ALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292485-A | Benzylpiperazine urea TRPV1 antagonistic and MOR agonistic double-target-point medicine, preparation method and application | 河南大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113292485-B | Benzyl piperazine urea TRPV1 antagonizing and MOR agonizing double-target medicine and its prepn and application | 河南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113292485-A | Benzylpiperazine urea TRPV1 antagonistic and MOR agonistic double-target-point medicine, preparation method and application | 河南大学 | 2021-08-24 | — | — | CN | disclosed |
| US-20030087913-A1 | Solid pharmaceutical agent formulation for a piperazine urea derivative | SCHERING AG (DE) | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087913-A1 | Solid pharmaceutical agent formulation for a piperazine urea derivative | SLC14A1, UTS2R, SP1 | SIGMAR1 386/4885ALDH1A1 1795/4885KMT2A 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.