Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947411 | 1.00 | SIGMAR1 (0.54) | SIGMAR1PPARGPPARASMPD1PTGES | |
| SCHEMBL6942964 | 0.87 | REN (0.44) | SIGMAR1PPARGPPARA | |
| SCHEMBL6942961 | 0.87 | REN (0.44) | SIGMAR1PPARGPPARA | |
| SCHEMBL6940727 | 0.85 | MTNR1A (0.54) | SIGMAR1SMPD1 | |
| SCHEMBL6940732 | 0.85 | MTNR1A (0.54) | SIGMAR1SMPD1 | |
| SCHEMBL7076864 | 0.84 | PPARA (0.42) | SIGMAR1PPARGPPARA | |
| SCHEMBL7076862 | 0.84 | PPARA (0.42) | SIGMAR1PPARGPPARA | |
| SCHEMBL6940648 | 0.82 | TUBB4A (0.54) | PPARGPPARA | |
| SCHEMBL6940652 | 0.82 | TUBB4A (0.54) | PPARGPPARA | |
| SCHEMBL6941202 | 0.79 | PPARA (0.45) | SIGMAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |