Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953114 | 0.91 | NR3C2 (0.49) | NR3C2RECQLTDP1KMT2AMEN1 | |
| SCHEMBL6950023 | 0.85 | LMNA (0.46) | NR3C2RECQLTDP1KMT2AMEN1 | |
| SCHEMBL6945824 | 0.81 | NR3C2 (0.44) | NR3C2RECQLTDP1KMT2AMEN1 | |
| SCHEMBL6947856 | 0.79 | RECQL (0.45) | NR3C2RECQLTDP1KMT2AMEN1 | |
| SCHEMBL6948537 | 0.78 | PYGL (0.46) | ATMGPBAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9236272 | 0.77 | KMT2A (0.39) | NR3C2KMT2AMEN1ATMLMNA | |
| SCHEMBL6947702 | 0.77 | PYGM (0.53) | NR3C2KMT2A | |
| SCHEMBL9236352 | 0.76 | PYGM (0.47) | KMT2AMEN1ATM | |
| SCHEMBL6949624 | 0.75 | KDM4E (0.47) | NR3C2RECQLTDP1KMT2AMEN1 | |
| SCHEMBL6945482 | 0.75 | CACNA1B (0.48) | KMT2AMEN1ATMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |