Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945774 | 0.92 | ALOX15 (0.44) | RECQLTDP1LMNASMN1; SMN2NR3C2 | |
| SCHEMBL6949414 | 0.90 | PYGM (0.49) | RECQLTDP1NR3C2KMT2AMEN1 | |
| SCHEMBL6945824 | 0.86 | NR3C2 (0.44) | RECQLTDP1LMNASMN1; SMN2NR3C2 | |
| SCHEMBL6950023 | 0.86 | LMNA (0.46) | RECQLTDP1LMNASMN1; SMN2NR3C2 | |
| SCHEMBL6952044 | 0.83 | PYGM (0.50) | NR3C2GPBAR1ALOX15 | |
| SCHEMBL6945485 | 0.79 | NR3C2 (0.51) | RECQLTDP1LMNASMN1; SMN2NR3C2 | |
| SCHEMBL6949624 | 0.78 | KDM4E (0.47) | RECQLTDP1LMNASMN1; SMN2NR3C2 | |
| SCHEMBL6953545 | 0.78 | PYGM (0.49) | RECQLTDP1NR3C2KMT2AMEN1 | |
| SCHEMBL6947702 | 0.77 | PYGM (0.53) | NR3C2KMT2A | |
| SCHEMBL7074756 | 0.74 | ALOX15 (0.41) | SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |