Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.46 |
| ▸ | PYGM | P11217 | 10/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949888 | 0.91 | PYGM (0.60) | PYGLPYGMGPBAR1 | |
| SCHEMBL6945485 | 0.78 | NR3C2 (0.51) | GPBAR1ALDH1A1ATMLMNASMN1; SMN2 | |
| SCHEMBL6949655 | 0.76 | PYGL (0.44) | PYGLPYGMKDM4EALDH1A1GLA | |
| SCHEMBL6948535 | 0.75 | CACNA1B (0.53) | KDM4EALDH1A1GAALMNA | |
| SCHEMBL6950023 | 0.75 | LMNA (0.46) | PYGLPYGMGPBAR1KDM4EALDH1A1 | |
| SCHEMBL6945774 | 0.74 | ALOX15 (0.44) | PYGLPYGMGPBAR1KDM4EALDH1A1 | |
| SCHEMBL6951169 | 0.74 | NR3C2 (0.43) | PYGLPYGMGPBAR1KDM4EALDH1A1 | |
| SCHEMBL6945824 | 0.73 | NR3C2 (0.44) | PYGLPYGMGPBAR1KDM4EALDH1A1 | |
| SCHEMBL6951439 | 0.72 | LMNA (0.44) | PYGLPYGMGPBAR1KDM4EALDH1A1 | |
| SCHEMBL11691222 | 0.72 | PYGL (0.56) | PYGLPYGMKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |