Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596023 | 0.75 | KDM4E (0.38) | ALDH1A1MAPTATMKCNJ1KCNH2 | |
| SCHEMBL532382 | 0.74 | MAPT (0.36) | ALDH1A1LMNAMAPTATMKCNJ1 | |
| SCHEMBL532247 | 0.72 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTATMKCNJ1 | |
| SCHEMBL532457 | 0.69 | BRD4 (0.37) | ALDH1A1MAPTHTR6L3MBTL1SMN1; SMN2 | |
| SCHEMBL13679140 | 0.64 | HTR6 (0.50) | ALDH1A1LMNAMAPTHTR6ATM | |
| SCHEMBL4573720 | 0.64 | KCNJ1 (0.65) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL377559 | 0.63 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL14782744 | 0.63 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTKDM4EHTT | |
| SCHEMBL15987432 | 0.62 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTKCNJ1KCNH2 | |
| SCHEMBL7465747 | 0.62 | L3MBTL1 (0.44) | ALDH1A1LMNAMAPTHTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653473-B2 | Nucleotide sequences for use as diagnostic tool in genetic analysis | EPOCH BIOSCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | ALDH1A1 2350/4885LMNA 1086/4885MAPT 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.