Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Formaldehyde. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446139 | 0.96 | CYP2A6 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| SCHEMBL339169 | 0.96 | CYP2A6 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Methyl Alcohol SCHEMBL8332469 | 0.93 | TSHR (0.46) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Potassium Ion SCHEMBL3209452 | 0.93 | CYP2A6 (0.48) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Sulfuric Acid SCHEMBL28146197 | 0.81 | TSHR (0.44) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| SCHEMBL3844980 | 0.81 | CYP2A6 (0.56) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Formaldehyde SCHEMBL9143924 | 0.81 | CA1 (0.39) | CYP2A6TSHRALDH1A1TDP1NR1I2 | |
| Formaldehyde SCHEMBL1033922 | 0.81 | CYP1A2 (0.47) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Formaldehyde SCHEMBL2859235 | 0.80 | NR1I2 (0.39) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 | |
| Formaldehyde SCHEMBL22158450 | 0.79 | CYP1A2 (0.46) | CYP2A6TSHRCYP1A2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118127850-A | Modified styrene-acrylic AKD composite surface sizing agent and preparation method thereof | 广东腾龙化工科技有限公司 | 2024-06-04 | — | — | CN | claimed |
| WO-2024109431-A1 | INSECTICIDAL PREPARATION CONTAINING META-DIAMIDE COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-117894980-A | Asphalt resin-based hard carbon composite material and preparation method and application thereof | 云南坤天新能源有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117052493-A | Low-cost compressed air combined heat and power generation system based on heat-conducting oil mortar heat accumulation | 中国电建集团江西省电力设计院有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-114680112-B | Mixed weeding composition containing dicamba, cyclosulfamide and atrazine and application thereof | 山东省联合农药工业有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-115336828-A | Antistatic and oilproof work glove and preparation method thereof | 上海赛立特安全用品有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-113533117-A | Method for measuring retention of impregnation liquid medicine on surface of plant leaf | 深圳诺普信农化股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-111937882-A | Compound water dispersible granule and preparation method thereof | 郑州农达生化制品有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-111820226-A | Compound synergistic composition containing penconazole and shenqinmycin | 邢慧君 | 2020-10-27 | — | — | CN | claimed |
| CN-110800758-A | Light calcium carbonate-containing bactericidal composition, preparation method and application thereof | 柳州市惠农化工有限公司 | 2020-02-18 | — | — | CN | claimed |
| CN-118177212-A | Weeding composition containing clomazone and mesosulfuron and application thereof | 河北省农林科学院植物保护研究所 | 2024-06-14 | — | — | CN | disclosed |
| CN-118127850-A | Modified styrene-acrylic AKD composite surface sizing agent and preparation method thereof | 广东腾龙化工科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024109431-A1 | INSECTICIDAL PREPARATION CONTAINING META-DIAMIDE COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-118077702-A | Insecticidal preparation containing metadiamide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117894980-A | Asphalt resin-based hard carbon composite material and preparation method and application thereof | 云南坤天新能源有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-0498231-B2 | Biocidal and agrochemical suspensions | HUNTSMAN INT LLC (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0498231-B1 | Biocidal and agrochemical suspensions | ALBRIGHT & WILSON UK LTD (GB) | 1997-05-02 | — | — | EP | disclosed |
| EP-0498231-A1 | Biocidal and agrochemical suspensions | ALBRIGHT & WILSON UK LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| US-5118583-A | Storage stability | MITSUBISHI PAPER MILLS LIMITED (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4041193-A | APPLYING AN ADHESIVE CONTAINING A SODIUM OR POTASSIUM SALT OF NAPHTHALENESULFONATE-FORMALDEHYDE CONDENSATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |