SCHEMBL6950447

SCHEMBL6950447

COc1ccc(CC[C@H](N)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.57
LDHA P00338 1/20 0.57
GRM8 O00222 1/20 0.55
GRM6 O15303 1/20 0.55
GRM4 Q14833 1/20 0.55
ALDH1A1 P00352 2/20 0.52
SLC1A5 Q15758 1/20 0.52
F2RL1 P55085 1/20 0.51
TAAR1 Q96RJ0 1/20 0.50
TPH1 P17752 2/20 0.49
GRIK1 P39086 1/20 0.49
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
GRIA4 P48058 1/20 0.49
GRIK2 Q13002 1/20 0.49
GRIK3 Q13003 1/20 0.49
FFAR1 O14842 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6942606 1.00 KIF11 (0.57) KIF11LDHAGRM8GRM6GRM4
SCHEMBL18071078 1.00 KIF11 (0.57) KIF11LDHAGRM8GRM6GRM4
SCHEMBL2926805 0.90 KIF11 (0.55) KIF11LDHAGRM8GRM6GRM4
SCHEMBL1238414 0.90 KIF11 (0.55) KIF11LDHAGRM8GRM6GRM4
SCHEMBL28463183 0.90 KIF11 (0.55) KIF11LDHAGRM8GRM6GRM4
SCHEMBL28463903 0.89 KIF11 (0.53) KIF11LDHAGRM8GRM6GRM4
SCHEMBL10419544 0.89 KIF11 (0.53) KIF11LDHAGRM8GRM6GRM4
SCHEMBL28463907 0.89 KIF11 (0.53) KIF11LDHAGRM8GRM6GRM4
SCHEMBL10420495 0.88 KIF11 (0.52) KIF11LDHAGRM8GRM6GRM4
SCHEMBL28467284 0.88 KIF11 (0.52) KIF11LDHAGRM8GRM6GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION WASHINGTON UNIVERSITY 2025-05-29 US claimed
US-20220380407-A1 COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS WASHINGTON UNIVERSITY (US) 2022-12-01 US claimed
EP-3989997-A1 COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS Washington University (US) 2022-05-04 EP claimed
US-12590123-B2 Compounds and methods for treating cancer, viral infections, and allergic conditions WASHINGTON UNIVERSITY (US) 2026-03-31 US disclosed
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION WASHINGTON UNIVERSITY 2025-05-29 US disclosed
EP-4433495-A1 PEPTIDES AND USES THEREOF Preveceutical Medical Inc. (CA) 2024-09-25 EP disclosed
US-20240301023-A1 PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2024-09-12 US disclosed
WO-2024148312-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-11 WO disclosed
US-11732007-B2 Therapeutic compounds and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-22 US disclosed
WO-2023089542-A1 PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2023-05-25 WO disclosed
US-20220380407-A1 COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS WASHINGTON UNIVERSITY (US) 2022-12-01 US disclosed
EP-3191113-B1 MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80 (B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS BRISTOL MYERS SQUIBB CO (US) 2019-11-06 EP disclosed
US-10344060-B2 Potent and selective inhibitors of Nav1.7 AMGEN INC. (US) 2019-07-09 US disclosed
EP-2970408-B1 POTENT AND SELECTIVE INHIBITORS OF NAV1.7 AMGEN INC (US) 2018-01-10 EP disclosed
US-20160024159-A1 POTENT AND SELECTIVE INHIBITORS OF NAV1.7 AMGEN INC. (US) 2016-01-28 US disclosed
EP-2970408-A2 POTENT AND SELECTIVE INHIBITORS OF Nav1.7 Amgen Inc. (US) 2016-01-20 EP disclosed
WO-2014165277-A2 POTENT AND SELECTIVE INHIBITORS OF Nav1.7 AMGEN INC. (US) 2014-10-09 WO disclosed
EP-0902011-B1 GAMMA-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME KANEKA CORP (JP) 2003-05-21 EP disclosed
US-5981794-A REACTING A BETA-BENZOYLACRYLIC ACID DERIVATIVE WITH A 1-ARYLETHYLAMINE DERIVATIVE KANEKA CORPORATION (JP) 1999-11-09 US disclosed
EP-0902011-A1 $g(g)-OXO-HOMOPHENYLALANINE DERIVATIVES AND PROCESS FOR PRODUCING HOMOPHENYLALANINE DERIVATIVES BY REDUCING THE SAME Kaneka Corporation (JP) 1999-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240301023-A1 PEPTIDES AND USES THEREOF OPRL1, OPRK1, OPRM1 KIF11 1440/4885LDHA 2547/4885GRM8 466/4885
US-10344060-B2 Potent and selective inhibitors of Nav1.7 SCN7A, SCN9A, SCN1A KIF11 3091/4885LDHA 3800/4885GRM8 745/4885
US-12590123-B2 Compounds and methods for treating cancer, viral infections, and allergic conditions TMPRSS2, TMPRSS4, F2RL3 KIF11 3300/4885LDHA 650/4885GRM8 3280/4885
US-20250171495-A1 MUTLI-TARGETED SERINE PROTEASE INHIBITORS FOR TREATMENT OF CANCER AND VIRAL INFECTION TMPRSS2, PRSS1, PRSS2 KIF11 4208/4885LDHA 295/4885GRM8 3159/4885
US-11732007-B2 Therapeutic compounds and methods MMP11, MMP13, MMP12 KIF11 329/4885LDHA 1758/4885GRM8 3477/4885
US-20220380407-A1 COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS TMPRSS2, PRSS1, PRSS2 KIF11 1345/4885LDHA 602/4885GRM8 3438/4885
US-20160024159-A1 POTENT AND SELECTIVE INHIBITORS OF NAV1.7 SCN7A, SCN9A, SCN1A KIF11 3091/4885LDHA 3800/4885GRM8 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.