Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189346 | 0.92 | ALDH1A1 (0.51) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL7188377 | 0.80 | CCNT1 (0.49) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL1395791 | 0.73 | OPA1 (0.53) | KMT2ALMNAALDH1A1USP2MAPT | |
| SCHEMBL7195540 | 0.70 | ADRB2 (0.48) | KMT2AALDH1A1POLBKDM4EHTT | |
| SCHEMBL10371558 | 0.70 | LMNA (0.48) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL17622891 | 0.68 | KMT2A (0.52) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL17067795 | 0.67 | ALDH1A1 (0.51) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL10338582 | 0.67 | TSHR (0.44) | KMT2ALMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL17622892 | 0.67 | KDM4E (0.46) | KMT2ALMNAALDH1A1USP2POLB | |
| SCHEMBL6663571 | 0.67 | LMNA (0.51) | KMT2ALMNAALDH1A1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-1275646-A1 | INDOLYLPYRROLE DERIVATIVES AND CELL DEATH INHIBITORS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087949-A1 | Indolylpyrrole derivatives and cell death inhibitors | AIFM1, BAX, CASP3 | KMT2A 3672/4885LMNA 121/4885ALDH1A1 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.