Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | SCD | O00767 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958325 | 0.81 | ADRA2C (0.46) | ADRA2CSCDMAPTGAAMEN1 | |
| SCHEMBL6960815 | 0.81 | HPGDS (0.47) | ADRA2CSCDHDAC8KDRHTT | |
| SCHEMBL6956103 | 0.79 | MAOA (0.48) | MAPTGAAHDAC8NPC1RAB9A | |
| SCHEMBL8824957 | 0.74 | SCD (0.39) | ADRA2CSCDMAPTGAAMEN1 | |
| SCHEMBL8824925 | 0.74 | GAA (0.38) | ADRA2CSCDMAPTGAAMEN1 | |
| SCHEMBL8825048 | 0.73 | GSK3A (0.43) | ADRA2CSCDMAPTGAAMEN1 | |
| SCHEMBL6964870 | 0.73 | ALDH1A1 (0.44) | SCDALDH1A1 | |
| SCHEMBL18033717 | 0.71 | PDGFRB (0.37) | MAPTGAAMEN1KMT2AHDAC8 | |
| SCHEMBL6958945 | 0.71 | CRHBP (0.42) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL554880 | 0.71 | ALDH1A1 (0.50) | GAAKMT2ARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |