Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967996 | 0.85 | AVPR2 (0.47) | DRD2DRD4DRD3ADRA1AHRH3 | |
| SCHEMBL6969043 | 0.83 | DRD3 (0.47) | DRD2DRD4DRD3ADRA1ATDP1 | |
| SCHEMBL6972375 | 0.81 | KDM4E (0.43) | DRD2DRD3ADRA1ATDP1KDM4E | |
| SCHEMBL6971119 | 0.76 | DRD2 (0.46) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6960079 | 0.75 | ALDH1A1 (0.48) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6958687 | 0.75 | DRD3 (0.46) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6959376 | 0.74 | HDAC1 (0.46) | TDP1ALDH1A1HPGDL3MBTL1HTR1A | |
| SCHEMBL6968459 | 0.74 | BCHE (0.56) | TDP1ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL6955542 | 0.73 | ALDH1A1 (0.43) | DRD2DRD4DRD3TDP1KDM4E | |
| SCHEMBL6969761 | 0.72 | L3MBTL1 (0.43) | DRD2DRD4DRD3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |