Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960605 | 0.82 | RBP4 (0.54) | RBP4POLBMAPTKDM4ETDP1 | |
| SCHEMBL6960722 | 0.81 | RBP4 (0.71) | RBP4POLBMAPTKDM4ETDP1 | |
| SCHEMBL6966493 | 0.81 | RBP4 (0.56) | RBP4POLBMAPTKDM4ETDP1 | |
| SCHEMBL6968075 | 0.81 | ALDH1A1 (0.40) | RBP4MAPTP2RX7KDM4ETDP1 | |
| SCHEMBL6966587 | 0.81 | RBP4 (0.52) | RBP4POLBMAPTKDM4ETDP1 | |
| SCHEMBL6960558 | 0.81 | MAPT (0.67) | RBP4MAPTKDM4ETDP1MAPK1 | |
| SCHEMBL6961204 | 0.80 | HTR1A (0.62) | RBP4MAPTRAB9AHTR1AHTR1D | |
| SCHEMBL6960101 | 0.79 | MAPT (0.59) | RBP4MAPTKDM4ETDP1MAPK1 | |
| SCHEMBL6965400 | 0.79 | RBP4 (0.60) | RBP4MAPTKDM4ETDP1MAPK1 | |
| SCHEMBL6967002 | 0.79 | RBP4 (0.76) | RBP4POLBMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |