SCHEMBL1989760

SCHEMBL1989760

CCCC[Si]([O])(OC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.35
NAAA Q02083 1/20 0.34
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704368 0.77 LTA4H (0.37) LTA4HNAAATSHRSMN1; SMN2
SCHEMBL2655578 0.77 LTA4H (0.37) LTA4HNAAATSHR
SCHEMBL706929 0.77 LTA4H (0.37) LTA4HNAAATSHRSMN1; SMN2
SCHEMBL6963975 0.76 SMN1; SMN2 (0.41) NAAATSHRSMN1; SMN2HTTCES2
SCHEMBL599107 0.76 NAAA (0.38) LTA4HNAAATSHRSMN1; SMN2HTT
SCHEMBL18107989 0.76 LTA4H (0.36) LTA4HNAAATSHRSMN1; SMN2L3MBTL1
SCHEMBL3481678 0.76 LTA4H (0.36) LTA4HNAAATSHR
SCHEMBL3482054 0.74 LTA4H (0.35) LTA4HNAAATSHRL3MBTL1
SCHEMBL3975498 0.74 LTA4H (0.35) LTA4HNAAATSHRSMN1; SMN2
SCHEMBL3481598 0.74 LTA4H (0.35) LTA4HNAAATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10131646-B2 Aromatic sulfonium salt compound, photoacid generator, resist composition, cationic polymerization initiator, and cationically polymerizable composition ADEKA CORPORATION (JP) 2018-11-20 US disclosed
US-20180079738-A1 AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2018-03-22 US disclosed
EP-3272744-A1 AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION Adeka Corporation (JP) 2018-01-24 EP disclosed
EP-2186799-B1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORP (JP) 2015-07-08 EP disclosed
US-9073854-B2 Aromatic sulfonium salt compound ADEKA CORPORATION (JP) 2015-07-07 US disclosed
EP-2502915-B1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORP (JP) 2015-03-18 EP disclosed
EP-2502915-A1 AROMATIC SULFONIUM SALT COMPOUND Adeka Corporation (JP) 2012-09-26 EP disclosed
US-8227624-B2 Aromatic sulfonium salt compound ADEKA CORPORATION (JP) 2012-07-24 US disclosed
US-20120136155-A1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORPORATION (JP) 2012-05-31 US disclosed
US-20110152540-A1 AROMATIC SULFONIUM SALT COMPOUND ADEKA CORPORATION (JP) 2011-06-23 US disclosed
EP-2186799-A1 AROMATIC SULFONIUM SALT COMPOUND Adeka Corporation (JP) 2010-05-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152540-A1 AROMATIC SULFONIUM SALT COMPOUND SLC43A1, SLC7A5, SPIN2B LTA4H 4386/4885NAAA 2947/4885TSHR 2150/4885
US-10131646-B2 Aromatic sulfonium salt compound, photoacid generator, resist composition, cationic polymerization initiator, and cationically polymerizable composition ASIC1, NOX5, SLC6A19 LTA4H 4405/4885NAAA 1598/4885TSHR 2893/4885
US-20120136155-A1 AROMATIC SULFONIUM SALT COMPOUND F12, ASIC1, SPIN1 LTA4H 3460/4885NAAA 1215/4885TSHR 2584/4885
US-20180079738-A1 AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION ASIC1, NOX5, SLC6A19 LTA4H 4405/4885NAAA 1598/4885TSHR 2893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.