Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952807 | 0.87 | SIGMAR1 (0.45) | PHF8KCNMA1KDM4CHPGDSKDM5A | |
| SCHEMBL6955809 | 0.85 | HPGDS (0.39) | PHF8KCNMA1KDM4CCPB2HPGDS | |
| SCHEMBL30741761 | 0.80 | HPGDS (0.50) | PHF8KCNMA1KDM4CCPB2CDK5 | |
| SCHEMBL6962477 | 0.76 | PHF8 (0.48) | PHF8KDM4CHPGDSCYP3A4CYP2D6 | |
| SCHEMBL9023871 | 0.75 | SIGMAR1 (0.44) | PHF8KDM4CHPGDSKDM5AKDM5B | |
| SCHEMBL6965586 | 0.74 | THRB (0.39) | PHF8CYP2A6CYP2B6CYP19A1LMNA | |
| SCHEMBL6974237 | 0.74 | CDK5 (0.51) | CDK5CDK5R1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6973877 | 0.74 | CYP3A4 (0.45) | PHF8KDM4CCPB2HPGDSKDM5A | |
| SCHEMBL5023714 | 0.73 | HPGDS (0.49) | PHF8KDM4CCDK5CDK5R1HPGDS | |
| SCHEMBL6972535 | 0.72 | KDM4C (0.38) | KDM4CHPGDSKDM5BCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |