Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965586 | 0.85 | THRB (0.39) | KDM4ETP53HTTLTA4H | |
| SCHEMBL6958763 | 0.82 | PHF8 (0.34) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL6955809 | 0.82 | HPGDS (0.39) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6968287 | 0.80 | NR1H2 (0.38) | ALDH1A1KDM4EYTHDC1LTA4H | |
| SCHEMBL6974237 | 0.78 | CDK5 (0.51) | ALDH1A1MEN1KMT2AHTTLTA4H | |
| SCHEMBL6968013 | 0.74 | KDM4C (0.40) | ADCY10IDO1L3MBTL1 | |
| SCHEMBL6952807 | 0.74 | SIGMAR1 (0.45) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL6972346 | 0.71 | PHF8 (0.38) | ALDH1A1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6973877 | 0.71 | CYP3A4 (0.45) | MAPTLTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6972535 | 0.70 | KDM4C (0.38) | MAPTL3MBTL1CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |