Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943621 | 0.93 | KDM4E (0.40) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6971137 | 0.92 | KDM4E (0.41) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL7953690 | 0.90 | KDM4E (0.40) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6969250 | 0.88 | NPC1 (0.43) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6975040 | 0.88 | LMNA (0.42) | KDM4EPKMLMNAGPR119TP53 | |
| Hydrochloric Acid SCHEMBL7943472 | 0.82 | ROCK2 (0.44) | CTSLCTSSCTSKROCK2 | |
| SCHEMBL6964406 | 0.82 | KDM4E (0.41) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6966451 | 0.81 | KDM4E (0.45) | KDM4EPKMLMNAYAP1GPR119 | |
| SCHEMBL6964195 | 0.81 | YAP1 (0.45) | TGFBR1KDM4EPKMLMNAYAP1 | |
| SCHEMBL6969887 | 0.80 | TGFBR1 (0.49) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |