Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 10/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.35 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975865 | 0.81 | TP53 (0.51) | MAOBGAA | |
| SCHEMBL6982879 | 0.79 | PDPK1 (0.49) | PLOD2MAOBGAA | |
| SCHEMBL6981786 | 0.79 | DYRK1A (0.49) | PLOD2MAOBPLOD3PLOD1 | |
| SCHEMBL6979450 | 0.78 | GAA (0.41) | STING1MAOBHSD17B1HSD17B2GAA | |
| SCHEMBL6983733 | 0.75 | DYRK1A (0.48) | MAOBGAA | |
| SCHEMBL6979367 | 0.75 | MAPT (0.57) | MAOBHSD17B1HSD17B2 | |
| SCHEMBL6979211 | 0.74 | RAB9A (0.58) | MAOBHSD17B1HSD17B2GAA | |
| SCHEMBL6979685 | 0.71 | GAA (0.47) | PLOD2PLOD3PLOD1GAA | |
| SCHEMBL6972014 | 0.71 | PLOD2 (0.41) | PLOD2MAOBPLOD3PLOD1HSD17B1 | |
| SCHEMBL6975976 | 0.71 | ACP1 (0.47) | MAOBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |