Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115209 | 0.91 | TBXAS1 (0.38) | POLBMAPTGNRHRALDH1A1RXFP1 | |
| SCHEMBL8115213 | 0.91 | TBXAS1 (0.38) | POLBMAPTGNRHRALDH1A1RXFP1 | |
| SCHEMBL6973833 | 0.89 | MAPT (0.36) | POLBMAPTGNRHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6973612 | 0.87 | KMT2A (0.39) | POLBMAPTALDH1A1RXFP1MEN1 | |
| SCHEMBL6969581 | 0.87 | ENPP2 (0.37) | MAPTLMNA | |
| SCHEMBL6968344 | 0.87 | ALDH1A1 (0.41) | POLBMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7083710 | 0.87 | KMT2A (0.38) | POLBMAPTGNRHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7081285 | 0.87 | MAPT (0.37) | POLBMAPTGNRHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7084614 | 0.87 | FKBP1A (0.38) | POLBMAPTGNRHRALDH1A1ATM | |
| SCHEMBL6973586 | 0.87 | CYP11B1 (0.41) | SMN1; SMN2MEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |