Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962479 | 0.73 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL6962467 | 0.73 | FKBP1A (0.39) | FKBP1A | |
| SCHEMBL6967183 | 0.72 | JAK2 (0.32) | SMYD3FKBP1A | |
| SCHEMBL6958233 | 0.72 | JAK2 (0.32) | SMYD3FKBP1A | |
| SCHEMBL6965719 | 0.72 | FKBP1A (0.37) | MEN1KMT2AFKBP1A | |
| SCHEMBL6965713 | 0.72 | FKBP1A (0.37) | MEN1KMT2AFKBP1A | |
| SCHEMBL6964692 | 0.72 | OPRK1 (0.45) | OPRK1TSHRFKBP1A | |
| SCHEMBL6962473 | 0.72 | OPRK1 (0.45) | OPRK1TSHRFKBP1A | |
| SCHEMBL6964491 | 0.71 | KDM4E (0.35) | SMYD3 | |
| SCHEMBL7234984 | 0.71 | L3MBTL1 (0.31) | SMYD3MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |