Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972367 | 0.86 | ALKBH1 (0.42) | ALKBH1MEP1AMEP1BGRM5VNN1 | |
| SCHEMBL6971033 | 0.80 | NR3C1 (0.42) | ALKBH1TSPOMEP1AMEP1BMEN1 | |
| SCHEMBL6973143 | 0.78 | MAPK1 (0.42) | TSPOMEP1AMEP1BVNN1NPC1 | |
| SCHEMBL6966662 | 0.74 | NPSR1 (0.44) | TSPOMEP1AMEP1BGRM5MEN1 | |
| SCHEMBL6959326 | 0.72 | VNN1 (0.51) | ALKBH1GRM5VNN1HSD17B10ALDH1A1 | |
| SCHEMBL6960286 | 0.70 | NR3C1 (0.38) | ALKBH1MEP1AMEP1BPDK1CHRM2 | |
| SCHEMBL6971432 | 0.70 | MEP1A (0.40) | ALKBH1MEP1AMEP1BGRM5VNN1 | |
| SCHEMBL6966121 | 0.69 | MEP1A (0.40) | ALKBH1MEP1AMEP1BGRM5VNN1 | |
| SCHEMBL31517446 | 0.69 | GRM5 (0.50) | ALKBH1GRM5MEN1KMT2ANPC1 | |
| SCHEMBL6963537 | 0.68 | PTGES (0.38) | ALKBH1MEP1AMEP1BNPC1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |