Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963537 | 0.87 | PTGES (0.38) | MAPK1NOTUMHPGDNPC1RAB9A | |
| SCHEMBL6966662 | 0.82 | NPSR1 (0.44) | NOTUMNPC1RAB9APOLBMEP1A | |
| SCHEMBL6971033 | 0.80 | NR3C1 (0.42) | NOTUMHPGDMEP1AMEP1BNR3C1 | |
| SCHEMBL6971432 | 0.79 | MEP1A (0.40) | HPGDNPC1RAB9APOLBMAPK14 | |
| SCHEMBL6966121 | 0.79 | MEP1A (0.40) | HPGDNPC1RAB9APOLBMAPK14 | |
| SCHEMBL6966037 | 0.78 | ALKBH1 (0.43) | NOTUMNPC1MEP1AMEP1BTSPO | |
| SCHEMBL6955000 | 0.77 | PTGES (0.38) | MAPK14MEP1AMEP1BNR3C1VNN1 | |
| SCHEMBL6955361 | 0.76 | PTGES (0.37) | MAPK14MEP1AMEP1BVNN1 | |
| SCHEMBL6969060 | 0.72 | ALDH1A1 (0.40) | MEP1AMEP1BNR3C1VNN1 | |
| SCHEMBL6964408 | 0.72 | ALDH1A1 (0.43) | MEP1AMEP1BNR3C1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |