Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099901 | 0.80 | CCR2 (0.41) | CCR2CCR5 | |
| SCHEMBL6969892 | 0.80 | CCR2 (0.39) | CCR2CCR5 | |
| SCHEMBL6961025 | 0.79 | LMNA (0.36) | LMNA | |
| SCHEMBL6965327 | 0.77 | VCP (0.37) | CCR2CCR5 | |
| SCHEMBL6969196 | 0.77 | LMNA (0.37) | LMNA | |
| SCHEMBL6973911 | 0.73 | CCR2 (0.41) | CCR2CCR5 | |
| SCHEMBL6962251 | 0.73 | TDP1 (0.38) | LMNA | |
| SCHEMBL7082337 | 0.72 | LMNA (0.36) | LMNA | |
| SCHEMBL6970235 | 0.71 | HSP90B1 (0.31) | LMNA | |
| SCHEMBL6967291 | 0.71 | ALOX12 (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |