Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973417 | 0.93 | MAPT (0.37) | HSP90AA1HSP90B1ENPP2KDM4EALDH1A1 | |
| SCHEMBL8343030 | 0.90 | LMNA (0.40) | ENPP2MEN1KMT2ATP53 | |
| SCHEMBL6974458 | 0.90 | S1PR3 (0.38) | ENPP2KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7082531 | 0.86 | HRH1 (0.34) | HSP90AA1HSP90B1KDM4EALDH1A1MEN1 | |
| SCHEMBL6970557 | 0.86 | MEN1 (0.34) | HSP90AA1HSP90B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6968985 | 0.86 | KDM4E (0.38) | ENPP2KDM4EMAPTP2RX3 | |
| SCHEMBL7084635 | 0.85 | ADRA1D (0.35) | HSP90AA1HSP90B1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6973437 | 0.85 | MEN1 (0.40) | ALDH1A1HPGDMEN1KMT2ATP53 | |
| SCHEMBL6970195 | 0.85 | TLR7 (0.35) | HSP90B1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7082928 | 0.85 | HRH1 (0.36) | HSP90B1KDM4EALDH1A1S1PR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |