Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980884 | 0.77 | BRD4 (0.31) | — | |
| SCHEMBL6982285 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2G6PDIDE | |
| SCHEMBL7948146 | 0.67 | PTGS2 (0.32) | — | |
| SCHEMBL7948151 | 0.61 | LMNA (0.36) | — | |
| SCHEMBL7821251 | 0.57 | ENPP2 (0.35) | SMN1; SMN2G6PDIDE | |
| SCHEMBL17378560 | 0.54 | G6PD (0.36) | SMN1; SMN2G6PDIDE | |
| SCHEMBL15739728 | 0.54 | ROCK1 (0.52) | — | |
| SCHEMBL6829782 | 0.53 | ENPP2 (0.46) | SMN1; SMN2 | |
| SCHEMBL862980 | 0.53 | POLB (0.73) | SMN1; SMN2 | |
| SCHEMBL2376239 | 0.53 | ENPP2 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131321-B1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | LILLY CO ELI (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-6329366-B1 | HETEROCYCLIC, PIPERIDINE, INDOLE DERIVITIVES FOR TREATMENT OF NERVOUS SYSTEM DISORDERS AND SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |