Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948146 | 0.86 | PTGS2 (0.32) | BRD4 | |
| SCHEMBL6974957 | 0.77 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL6527029 | 0.74 | BRD4 (0.33) | BRD4 | |
| SCHEMBL6527027 | 0.66 | KCNH2 (0.34) | BRD4 | |
| SCHEMBL7948151 | 0.64 | LMNA (0.36) | BRD4 | |
| SCHEMBL6502022 | 0.63 | MEN1 (0.41) | — | |
| SCHEMBL31016286 | 0.62 | NPBWR1 (0.38) | BRD4 | |
| SCHEMBL28347309 | 0.60 | LRRK2 (0.41) | — | |
| SCHEMBL7821251 | 0.59 | ENPP2 (0.35) | BRD4 | |
| SCHEMBL1428902 | 0.57 | ENPP2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131321-B1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | LILLY CO ELI (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-6329366-B1 | HETEROCYCLIC, PIPERIDINE, INDOLE DERIVITIVES FOR TREATMENT OF NERVOUS SYSTEM DISORDERS AND SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |