SCHEMBL502464

SCHEMBL502464

CC(C)(C)c1cc2c(c(C(C)(C)C)c1)OC(=O)C2

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABBR2 O75899 1/20 0.43
GABBR1 Q9UBS5 1/20 0.43
ELANE P08246 1/20 0.34
CD69 Q07108 1/20 0.34
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692994 1.00 GABBR2 (0.43) GABBR2GABBR1ELANECD69CA12
SCHEMBL27498145 0.85 GABBR2 (0.42) GABBR2GABBR1ELANECD69
SCHEMBL18050475 0.84 POLB (0.35) GABBR2GABBR1ELANECD69CA12
SCHEMBL25523060 0.83 SMN1; SMN2 (0.38) GABBR2GABBR1CA2
SCHEMBL6313837 0.79 CA2 (0.43) ELANECA12CA2CA9
SCHEMBL6976097 0.79 MAPT (0.36) ELANECD69CA12CA2CA9
SCHEMBL19648626 0.75 ELANE (0.36) GABBR2GABBR1ELANECD69
SCHEMBL532627 0.75 ELANE (0.36) GABBR2GABBR1ELANECD69
SCHEMBL29488109 0.75 ELANE (0.36) GABBR2GABBR1ELANECD69
SCHEMBL10997770 0.74 GABBR2 (0.37) GABBR2GABBR1ELANECD69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141533-A1 LACTONE COMPOUND FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
CN-115175958-A Polyolefin compositions 巴斯夫欧洲公司 2022-10-11 CN disclosed
US-11453742-B2 Methods for reducing aldehyde emissions in polyurethane foams DOW GLOBAL TECHNOLOGIES LLC (US) 2022-09-27 US disclosed
US-8518302-B2 Stabilization of organic materials BASF SE (DE) 2013-08-27 US disclosed
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS GERSTER MICHELE (CH) 2012-04-12 US disclosed
US-8105504-B2 Stabilization of organic materials BASF SE (DE) 2012-01-31 US disclosed
EP-1786859-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2011-06-08 EP disclosed
CN-101341207-B Composition, optical film, method for producing optical film, polarizing plate, and liquid crystal display device KONICA MINOLTA OPTO INC 2011-02-09 CN disclosed
CN-101010369-B Stabilization of organic materials CIBA SC HOLDING AG 2010-12-22 CN disclosed
US-7854864-B2 Method for manufacturing an optical film having a convexoconcave structure KONICA MINOLTA OPTO, INC. (JP) 2010-12-21 US disclosed
EP-1015518-A1 ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF Ciba SC Holding AG (CH) 2000-07-05 EP disclosed
WO-2000024736-A1 OXOBENZOFURANYLIDE-DIHYDROINDOLONE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-04 WO disclosed
WO-1999052909-A2 DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL CIBA SPECIALTY CHEMICAL HOLDING INC. (CH) 1999-10-21 WO disclosed
WO-1999013007-A1 ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-03-18 WO disclosed
EP-0891989-A1 Modified polymers containing methylene groups PCD Polymere AG (AT) 1999-01-20 EP disclosed
CN-1041415-C 3-arylbenzofuranone stabilizers and uses thereof CIBA GEIGY AG (CH) 1998-12-30 CN disclosed
CN-1178527-A Biphenyl-substituted triazines as light stabilizers CIBA GEIGY AG (CH) 1998-04-08 CN disclosed
US-5679634-A Use of dihydrobenzofuranones as perfuming ingredients FIRMENICH S.A. (CH) 1997-10-21 US disclosed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP disclosed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088869-A1 STABILIZATION OF ORGANIC MATERIALS LPO, AOX1, SOD1 GABBR2 4068/4885GABBR1 3656/4885ELANE 2070/4885
US-20230141533-A1 LACTONE COMPOUND MRPS22, YWHAZ, RPLP1 GABBR2 4189/4885GABBR1 4326/4885ELANE 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.