Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974917 | 0.86 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL6984711 | 0.86 | RAB9A (0.42) | KMT2ASMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL6175938 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAMAPTHSD17B10 | |
| SCHEMBL19353009 | 0.78 | KMT2A (0.51) | KMT2ASMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL6985419 | 0.76 | KMT2A (0.41) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6984916 | 0.76 | KMT2A (0.41) | KMT2AMEN1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL6982440 | 0.74 | PDK1 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1L3MBTL1 | |
| SCHEMBL16429902 | 0.73 | KMT2A (0.64) | KMT2ASMN1; SMN2MEN1ALDH1A1L3MBTL1 | |
| SCHEMBL6171559 | 0.72 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1L3MBTL1GAA | |
| SCHEMBL3459387 | 0.72 | L3MBTL1 (0.64) | KMT2ASMN1; SMN2MEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |