Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982667 | 0.90 | NR3C1 (0.41) | ALDH1A1NR3C1TAS2R14MEN1HPGD | |
| SCHEMBL6981554 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1HPGDKMT2ALMNA | |
| SCHEMBL6986002 | 0.88 | RXRA (0.45) | ALDH1A1TAS2R14MEN1HPGDKMT2A | |
| SCHEMBL6987767 | 0.86 | TP53 (0.42) | ALDH1A1NR3C1LMNAGAAUSP2 | |
| SCHEMBL6982999 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAGAAMAPT | |
| SCHEMBL6977634 | 0.85 | NR3C1 (0.53) | ALDH1A1NR3C1MEN1HPGDKMT2A | |
| SCHEMBL6987632 | 0.85 | ALDH1A1 (0.39) | ALDH1A1NR3C1TAS2R14MEN1HPGD | |
| SCHEMBL6981987 | 0.85 | PTGER4 (0.38) | ALDH1A1NR3C1MEN1HPGDKMT2A | |
| SCHEMBL6983751 | 0.84 | NR3C1 (0.40) | ALDH1A1NR3C1MEN1HPGDKMT2A | |
| SCHEMBL6986008 | 0.83 | MEN1 (0.39) | ALDH1A1MEN1HPGDKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |