Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982234 | 0.87 | TP53 (0.41) | TP53LMNAUSP2ALDH1A1L3MBTL1 | |
| SCHEMBL6986000 | 0.87 | NR3C1 (0.36) | LMNAALDH1A1L3MBTL1GAANR3C1 | |
| SCHEMBL6982667 | 0.86 | NR3C1 (0.41) | TP53KEAP1NFE2L2LMNAUSP2 | |
| SCHEMBL7407619 | 0.86 | MAPT (0.34) | TP53PTGER1ALDH1A1HCRTR2KDM1A | |
| SCHEMBL6977636 | 0.86 | ALDH1A1 (0.42) | TP53LMNAUSP2ALDH1A1GAA | |
| SCHEMBL6982692 | 0.86 | L3MBTL1 (0.38) | LMNAALDH1A1L3MBTL1KDM1ANR3C1 | |
| SCHEMBL6987763 | 0.86 | NR3C1 (0.47) | LMNAUSP2ALDH1A1HCRTR2KDM1A | |
| SCHEMBL6985399 | 0.85 | NOTUM (0.36) | LMNAUSP2ALDH1A1L3MBTL1GAA | |
| SCHEMBL6985613 | 0.84 | CCR5 (0.37) | LMNAUSP2ALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL6979151 | 0.83 | USP14 (0.35) | USP2ALDH1A1L3MBTL1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |