Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969387 | 0.74 | LMNA (0.34) | ALDH1A1MEN1KMT2AATMTAS2R8 | |
| SCHEMBL6980296 | 0.65 | GLA (0.42) | ALDH1A1KMT2ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL6978808 | 0.64 | — | — | |
| SCHEMBL6976719 | 0.62 | POLB (0.59) | — | |
| SCHEMBL22271029 | 0.62 | ADAMTS4 (0.46) | TAS2R8LMNA | |
| SCHEMBL6977732 | 0.61 | HSD17B10 (0.40) | ALDH1A1MEN1KMT2AATMMAPT | |
| SCHEMBL28931395 | 0.61 | CRHBP (0.39) | ALDH1A1MEN1KMT2ATAS2R8LMNA | |
| SCHEMBL6979312 | 0.61 | ALDH1A1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL6976712 | 0.61 | USP2 (0.43) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL6979452 | 0.60 | RAB9A (0.35) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |