Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971479 | 0.78 | CTSD (0.38) | RAB9AALDH1A1GABRA5PTGS2L3MBTL1 | |
| SCHEMBL6979447 | 0.78 | RAB9A (0.34) | RAB9AALDH1A1GABRA5L3MBTL1POLB | |
| SCHEMBL6978425 | 0.77 | CHRNB2 (0.42) | POLB | |
| SCHEMBL6975255 | 0.74 | — | — | |
| SCHEMBL6976719 | 0.72 | POLB (0.59) | POLB | |
| SCHEMBL6979018 | 0.69 | POLB (0.54) | POLB | |
| SCHEMBL6981221 | 0.68 | POLB (0.45) | POLB | |
| SCHEMBL6974839 | 0.68 | ALDH1A1 (0.41) | RAB9AALDH1A1 | |
| SCHEMBL6975710 | 0.67 | GABRA5 (0.35) | RAB9AALDH1A1GABRA5PTGS2L3MBTL1 | |
| SCHEMBL23366325 | 0.65 | PTGS2 (0.47) | ALDH1A1GABRA5PTGS2L3MBTL1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |