Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980741 | 0.92 | HPGD (0.47) | ALDH1A1KMT2AHPGDCYP1A2CYP3A4 | |
| SCHEMBL7123772 | 0.89 | SMN1; SMN2 (0.51) | ALDH1A1KMT2AHPGDCYP1A2CYP3A4 | |
| SCHEMBL6979916 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2APKMHPGDHSD17B10 | |
| SCHEMBL6973351 | 0.75 | DRD2 (0.52) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6976438 | 0.74 | NPC1 (0.45) | KMT2ALMNAGAA | |
| SCHEMBL6976878 | 0.72 | HSD11B1 (0.51) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL7466468 | 0.70 | HPGD (0.71) | ALDH1A1KMT2AHPGDCYP1A2CYP3A4 | |
| SCHEMBL6972446 | 0.69 | HSD17B10 (0.48) | ALDH1A1HPGDHSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6975639 | 0.69 | MAP3K12 (0.49) | KMT2AMEN1LMNA | |
| SCHEMBL786692 | 0.69 | ALDH1A1 (0.76) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |