Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976878 | 0.88 | HSD11B1 (0.51) | RAB9AKMT2ALMNAGAAHSD11B1 | |
| SCHEMBL7123772 | 0.86 | SMN1; SMN2 (0.51) | NPC1RAB9AKMT2A | |
| SCHEMBL6972446 | 0.83 | HSD17B10 (0.48) | NPC1RAB9ALMNAHSD11B1MAPK7 | |
| SCHEMBL6972466 | 0.81 | ALDH1A1 (0.44) | RAB9AKMT2ALMNAGAATRPC6 | |
| SCHEMBL6981137 | 0.78 | SMN1; SMN2 (0.54) | KMT2AGAA | |
| SCHEMBL6981142 | 0.78 | GLA (0.55) | KMT2A | |
| SCHEMBL6980741 | 0.76 | HPGD (0.47) | KMT2ALMNAGAAMGLL | |
| SCHEMBL6973351 | 0.76 | DRD2 (0.52) | KMT2ALMNAMGLL | |
| SCHEMBL6976781 | 0.74 | ALDH1A1 (0.43) | NPC1RAB9AKMT2ALMNA | |
| SCHEMBL6979916 | 0.74 | ALDH1A1 (0.43) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5948786-A | BLOCKING TUMOR NECROSIS FACTOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-09-07 | — | — | US | disclosed |