Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980741 | 0.90 | HPGD (0.47) | SMN1; SMN2KMT2AHPGDALDH1A1MCHR1 | |
| SCHEMBL6980066 | 0.89 | ALDH1A1 (0.48) | SMN1; SMN2KMT2AHPGDALDH1A1MCHR1 | |
| SCHEMBL6979916 | 0.88 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AHPGDALDH1A1MCHR1 | |
| SCHEMBL6976438 | 0.86 | NPC1 (0.45) | RAB9AKMT2ANPC1 | |
| SCHEMBL6976878 | 0.85 | HSD11B1 (0.51) | RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6972446 | 0.80 | HSD17B10 (0.48) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL6972466 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL6981137 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL6981142 | 0.75 | GLA (0.55) | KMT2ATSHR | |
| SCHEMBL6973351 | 0.73 | DRD2 (0.52) | DRD2DRD3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003095951-A | THERAPEUTIC AGENT FOR RHEUMATOID ARTHRITIS | SUMITOMO PHARMACEUT CO LTD | 2003-04-03 | — | — | JP | disclosed |