Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984282 | 0.90 | HSD17B10 (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2HPGD | |
| SCHEMBL6981026 | 0.90 | AGTR2 (0.40) | ALDH1A1LMNAAGTR2CYP2C9TSHR | |
| SCHEMBL6984622 | 0.88 | AGTR2 (0.39) | ALDH1A1LMNAAGTR2CYP1A2TSHR | |
| SCHEMBL6986283 | 0.85 | HTR2C (0.42) | AGTR2 | |
| SCHEMBL6988437 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNATSHRNPC1RAB9A | |
| SCHEMBL6986113 | 0.84 | AGTR2 (0.41) | ALDH1A1LMNAAGTR2KMT2ASMN1; SMN2 | |
| SCHEMBL6983767 | 0.83 | DRD4 (0.41) | ALDH1A1LMNAAGTR2TSHRNPC1 | |
| SCHEMBL6986237 | 0.83 | AGTR2 (0.39) | ALDH1A1LMNAAGTR2NPSR1MAPT | |
| SCHEMBL6988584 | 0.82 | USP2 (0.43) | ALDH1A1LMNAAGTR2TSHRRAB9A | |
| SCHEMBL6984642 | 0.81 | HRH3 (0.39) | AGTR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |