Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981026 | 0.92 | AGTR2 (0.40) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6986283 | 0.88 | HTR2C (0.42) | — | |
| SCHEMBL6984622 | 0.88 | AGTR2 (0.39) | ALDH1A1SMN1; SMN2LMNAKMT2ABRD4 | |
| SCHEMBL6986237 | 0.85 | AGTR2 (0.39) | ALDH1A1LMNAMEN1KMT2APIK3CB | |
| SCHEMBL6981802 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6986113 | 0.85 | AGTR2 (0.41) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6983767 | 0.84 | DRD4 (0.41) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6984642 | 0.84 | HRH3 (0.39) | BRD4CFTR | |
| SCHEMBL6984282 | 0.83 | HSD17B10 (0.43) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6988584 | 0.83 | USP2 (0.43) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |