Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981802 | 0.90 | ALDH1A1 (0.42) | HSD17B10GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6981026 | 0.88 | AGTR2 (0.40) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6984622 | 0.86 | AGTR2 (0.39) | HSD17B10KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6986283 | 0.84 | HTR2C (0.42) | — | |
| SCHEMBL6988437 | 0.83 | ALDH1A1 (0.45) | GAAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6986113 | 0.82 | AGTR2 (0.41) | HSD17B10GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL6983767 | 0.82 | DRD4 (0.41) | HSD17B10KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6986237 | 0.81 | AGTR2 (0.39) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6988584 | 0.81 | USP2 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6984642 | 0.80 | HRH3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |