Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982528 | 0.91 | MRGPRX1 (0.47) | AVPR2OXTRAVPR1ANR3C1MAPT | |
| SCHEMBL6984143 | 0.90 | NR3C1 (0.37) | AVPR2OXTRAVPR1ANR3C1MAPT | |
| SCHEMBL6982945 | 0.84 | NR3C1 (0.36) | AVPR2OXTRAVPR1ANR3C1MAPT | |
| SCHEMBL6984843 | 0.82 | GAA (0.43) | NR3C1GAAALDH1A1NPC1RAB9A | |
| SCHEMBL6981833 | 0.81 | NR3C1 (0.51) | NR3C1MAPTLMNATP53GAA | |
| SCHEMBL6982761 | 0.81 | HDAC1 (0.35) | NR3C1MAPTATMGAAALDH1A1 | |
| SCHEMBL6981764 | 0.80 | METAP2 (0.42) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6982500 | 0.79 | SLC16A3 (0.48) | GAA | |
| SCHEMBL6984787 | 0.76 | ATM (0.48) | MAPTTP53ATMALDH1A1NPC1 | |
| SCHEMBL6985566 | 0.76 | PARP14 (0.40) | NR3C1MAPTTP53ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |