Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985322 | 0.89 | GAA (0.41) | NR3C1FPR1FPR2TSHRMEN1 | |
| SCHEMBL6982945 | 0.89 | NR3C1 (0.36) | NR3C1ATMFPR1FPR2DPP8 | |
| SCHEMBL6984143 | 0.87 | NR3C1 (0.37) | NR3C1ATMFPR1FPR2ALDH1A1 | |
| SCHEMBL6982761 | 0.87 | HDAC1 (0.35) | NR3C1ATMFPR1FPR2DPP8 | |
| SCHEMBL6980994 | 0.86 | RXRA (0.43) | ATMFPR1FPR2TSHRMEN1 | |
| SCHEMBL6978202 | 0.86 | ALDH1A1 (0.37) | NR3C1ATMFPR1FPR2DPP8 | |
| SCHEMBL6978509 | 0.86 | PTGER4 (0.40) | NR3C1ATMFPR1FPR2DPP8 | |
| SCHEMBL6986817 | 0.85 | THRB (0.42) | ATMFPR1FPR2TSHRALDH1A1 | |
| SCHEMBL6981035 | 0.84 | DPP8 (0.36) | NR3C1ATMFPR1FPR2DPP8 | |
| SCHEMBL6986437 | 0.84 | PTGER4 (0.41) | ATMFPR1FPR2DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |