Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940361 | 0.82 | ADAM17 (0.37) | BCHE | |
| SCHEMBL6980963 | 0.82 | MMP1 (0.36) | BCHE | |
| SCHEMBL6986604 | 0.80 | BMP1 (0.30) | — | |
| SCHEMBL6945603 | 0.79 | ADAM17 (0.38) | — | |
| SCHEMBL6987301 | 0.78 | BMP1 (0.34) | BCHE | |
| SCHEMBL6987276 | 0.76 | ADAM17 (0.36) | — | |
| SCHEMBL6981709 | 0.76 | BMP1 (0.38) | — | |
| SCHEMBL6986861 | 0.75 | MMP2 (0.34) | — | |
| SCHEMBL6989548 | 0.75 | BMP1 (0.35) | — | |
| SCHEMBL6987284 | 0.75 | ADAM17 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-10-29 | — | — | EP | disclosed |
| US-6239151-B1 | TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES, OSTEOARTHRITIS, RESPIRATORY DISEASES, TUMORS, CACHEXIA, CARDIOVASCULAR DISEASES, FEVER, HAEMORRHAGE AND SEPSIS, HYDRAZINE DERIVATIVES, | HOFFMANN-LA ROCHE INC. | 2001-05-29 | — | — | US | disclosed |