Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985322 | 0.86 | GAA (0.41) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6985371 | 0.84 | NR3C1 (0.44) | PKMNR3C1LMNAARALDH1A1 | |
| SCHEMBL6981761 | 0.83 | LIMK2 (0.40) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6980541 | 0.82 | HSD17B10 (0.48) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6983044 | 0.82 | NR3C1 (0.58) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6984554 | 0.80 | ALDH1A1 (0.44) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6982980 | 0.80 | PKM (0.39) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL7406048 | 0.80 | EEF2K (0.39) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6976883 | 0.80 | NR3C1 (0.38) | PKMTP53NR3C1MAPTLMNA | |
| SCHEMBL6983505 | 0.79 | NR3C1 (0.42) | PKMTP53NR3C1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |