Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983048 | 0.84 | NAMPT (0.41) | NR3C1ARALDH1A1LMNAHTT | |
| SCHEMBL6984554 | 0.84 | ALDH1A1 (0.44) | NR3C1ARSLC16A3L3MBTL1ALDH1A1 | |
| SCHEMBL6980541 | 0.84 | HSD17B10 (0.48) | NR3C1ARALDH1A1LMNAHTT | |
| SCHEMBL6985322 | 0.84 | GAA (0.41) | NR3C1ARALDH1A1LMNAPKM | |
| SCHEMBL6981761 | 0.82 | LIMK2 (0.40) | NR3C1ARALDH1A1LMNAPKM | |
| SCHEMBL7406048 | 0.82 | EEF2K (0.39) | NR3C1ARSLC16A3ALDH1A1LMNA | |
| SCHEMBL6982980 | 0.82 | PKM (0.39) | NR3C1ARALDH1A1LMNASLC22A12 | |
| SCHEMBL6976883 | 0.82 | NR3C1 (0.38) | NR3C1ARALDH1A1LMNASLC22A12 | |
| SCHEMBL6985366 | 0.80 | NR3C1 (0.66) | NR3C1ALDH1A1LMNA | |
| SCHEMBL6983505 | 0.79 | NR3C1 (0.42) | NR3C1ARSLC16A3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |