Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6982867 | 0.85 | KDM4E (0.44) | ALDH1A1MAPTPOLBRECQLKDM4E | |
| Hydrochloric Acid SCHEMBL6976894 | 0.83 | HRH3 (0.36) | ALDH1A1MAPTPOLBRECQLKDM4E | |
| Oxalic Acid SCHEMBL6978397 | 0.75 | PRCP (0.37) | ALDH1A1MAPTKDM4ECNR1HRH3 | |
| SCHEMBL6978399 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLBRECQLKDM4E | |
| Oxalic Acid SCHEMBL6969996 | 0.73 | KMT2A (0.46) | ALDH1A1MAPTPOLBKDM4EGAA | |
| SCHEMBL6970002 | 0.72 | HTR2A (0.34) | ALDH1A1MAPTCNR1HRH3HTR1A | |
| SCHEMBL8316992 | 0.65 | HRH3 (0.39) | ALDH1A1KDM4EL3MBTL1CNR1HRH3 | |
| Hydrochloric Acid SCHEMBL6984682 | 0.64 | DRD2 (0.58) | KDM4EHRH3HTR1AKCNH2DRD4 | |
| SCHEMBL6975602 | 0.63 | HTR1A (0.38) | ALDH1A1MAPTHTR1AHTR2ADRD3 | |
| SCHEMBL6975606 | 0.63 | HTR1A (0.38) | ALDH1A1MAPTHTR1AHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1065205-B1 | HETEROAROMATIC DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-1207159-A1 | Aromaheterocyclic derivatives as dopamine D4 receptor antagonists | TAISHO PHARMACEUTICAL CO. LTD (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-6291467-B1 | DOPAMINE D4 RECEPTOR ANTAGONIST COMPOUND HAVING AN ANTIPSYCHOTIC ACTION WITHOUT CAUSING EXTRAPYRAMIDAL DISEASES. | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-1065205-A1 | HETEROAROMATIC DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-01-03 | — | — | EP | disclosed |